Supplement Manufacturing Quality Control: GMP, ISO, and Beyond
Quality control is the foundation of supplement manufacturing. Here’s what GMP, ISO 22000, HACCP, and third-party testing mean for your brand.
GMP (Good Manufacturing Practice)
GMP is the foundation of supplement manufacturing. It covers:
- Facility design and sanitation
- Equipment maintenance and calibration
- Personnel training and hygiene
- Raw material sourcing and testing
- Production process controls
- Quality testing and release
- Documentation and record-keeping
Tocura: GMP certified by Turkish Ministry of Health. Annual external audits.
ISO 22000 (Food Safety Management)
ISO 22000 is an international standard for food safety management. It covers:
- Hazard analysis and critical control points (HACCP)
- Prerequisite programs (sanitation, pest control)
- Food safety policy and objectives
- Document control and record-keeping
- Continuous improvement
Tocura: ISO 22000:2018 certified. Annual external audits.
HACCP (Hazard Analysis and Critical Control Points)
HACCP is a systematic approach to food safety:
- Hazard analysis (biological, chemical, physical)
- Critical control points (CCPs) identification
- Monitoring procedures at each CCP
- Corrective actions for deviations
- Verification and validation
Tocura: HACCP implemented at every production stage. Real-time monitoring.
Third-Party Testing
Independent laboratory verification ensures product quality:
| Test | Frequency | What It Verifies |
|---|---|---|
| Potency | Every batch | Active ingredient levels match label claims |
| Purity | Every batch | No contaminants (heavy metals, pesticides, microbes) |
| Stability | Quarterly | Product maintains quality over shelf life |
| Microbial limits | Every batch | No harmful bacteria, yeast, mold |
| Dissolution | Every batch | Products disintegrate/release as expected |
Tocura’s Quality System
- GMP certified (Turkish Ministry of Health)
- ISO 22000:2018 certified
- HACCP implemented
- In-house quality lab (potency, purity, stability)
- Third-party testing (independent laboratory)
- Full traceability (raw material to finished product)
- Annual external audits
- Monthly internal audits
Why Quality Matters
- Consumer trust: 78% check certifications before buying
- Regulatory compliance: Required for market access
- Brand protection:Related: Turkey Directory 2026
Related: Start Brand Guide 2026
Related: Custom Formulation Guide 2026